Scientists at NIAID are progressing toward a faster, more practical way to screen people and animals for prion diseases, which have baffled researchers for decades. Background can become infectious and cause neurodegenerative disease. Here, four nerve cells in a mouse illustrate how infectious prion protein, in red, moves within cells along neurites—wire-like connections the nerve cells use to communicate with adjacent cells. Prion diseases, also known as transmissible spongiform encephalopathies (TSEs), are difficult to diagnose, untreatable, and ultimately fatal. Normally, prion protein molecules exist harmlessly in every mammal, but for reasons not fully understood, these protein molecules sometimes develop abnormalities and gather in clusters. Accumulation of these abnormal prion protein clusters is associated with tissue damage that leaves microscopic sponge-like holes in the brain. Prion diseases include sporadic Creutzfeldt-Jacob disease (CJD) and variant CJD in huma
Este blog é destinado aos curiosos e apaixonados pela ciência! Com uma linguagem simples você poderá se atualizar e conhecer um pouco deste mundo encantador. Administradores do Blog: Dr Benildo Sousa Cavada e Dra Kyria Santiago do Nascimento. Editores: Kyria S Nascimento, Benildo S Cavada e Cláudio Henrique Dahne (Graduando em Ciências Biológicas).