A close-up image of the microneedle array, which could delivery quantum dots into skin. [K.J. McHugh et al. Science Translational Medicine (2019)] Researchers headed by a team at the Massachusetts Institute of Technology (MIT) have created a microneedle platform using fluorescent microparticles called quantum dots (QD), which can deliver vaccines and at the same time invisibly encode vaccination history directly in the skin. The quantum dots are composed of nanocrystals, which emit near-infrared (NIR) light that can be detected by a specially equipped smartphone. Tests using the platform showed that QDs delivered to samples of human skin were still detectable after photobleaching that simulated five years of exposure sunlight, and they remained detectable for up to nine months when tested in rats. The researchers encapsulated their quantum dots in microspheres made of PMMA, a material that improves biocompatibility. [K.J. McHugh et al. Science Translational Medicine (2019)]...
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